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Stereoselective Synthesis of Cyclobutanes by Contraction of Pyrrolidines

[Image: see text] Here we report a contractive synthesis of multisubstituted cyclobutanes containing multiple stereocenters from readily accessible pyrrolidines using iodonitrene chemistry. Mediated by a nitrogen extrusion process, the stereospecific synthesis of cyclobutanes involves a radical path...

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Detalles Bibliográficos
Autores principales: Hui, Chunngai, Brieger, Lukas, Strohmann, Carsten, Antonchick, Andrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603356/
https://www.ncbi.nlm.nih.gov/pubmed/34748319
http://dx.doi.org/10.1021/jacs.1c10175