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Role of mammalian target of rapamycin complex 2 in primary and secondary liver cancer

The mammalian target of rapamycin (mTOR) acts in two structurally and functionally distinct protein complexes, mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). Upon deregulation, activated mTOR signaling is associated with multiple processes involved in tumor growth and metastasis. Compared with...

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Detalles Bibliográficos
Autores principales: Joechle, Katharina, Guenzle, Jessica, Hellerbrand, Claus, Strnad, Pavel, Cramer, Thorsten, Neumann, Ulf Peter, Lang, Sven Arke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603445/
https://www.ncbi.nlm.nih.gov/pubmed/34853640
http://dx.doi.org/10.4251/wjgo.v13.i11.1632