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Genome-wide CRISPR-Cas9 screening identifies that hypoxia-inducible factor-1a-induced CBX8 transcription promotes pancreatic cancer progression via IRS1/AKT axis

BACKGROUND: Pancreatic cancer (PC) is one of the most lethal malignancies worldwide. It is known that the proliferation of PC cells is a critical process in the disease. Previous studies have failed to identify the key genes associated with PC cell proliferation, using bioinformatic analysis, genome...

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Detalles Bibliográficos
Autores principales:	Teng, Bu-Wei, Zhang, Kun-Dong, Yang, Yu-Han, Guo, Zeng-Ya, Chen, Wei-Wei, Qiu, Zheng-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2021
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603463/ https://www.ncbi.nlm.nih.gov/pubmed/34853645 http://dx.doi.org/10.4251/wjgo.v13.i11.1709

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