Prostaglandin E(2) sensitizes the cough reflex centrally via EP3 receptor-dependent activation of NaV 1.8 channels

BACKGROUND: Cough hypersensitivity is a major characteristic feature associated with several types of cough, including chronic cough, but its underlying mechanisms remain to be fully understood. Inflammatory mediators, such as prostaglandin E(2) (PGE(2)), have been implicated in both peripheral indu...

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Detalles Bibliográficos
Autores principales: Al-Kandery, Al-Shaimaa A., Rao, Muddanna S., El-Hashim, Ahmed Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603488/
https://www.ncbi.nlm.nih.gov/pubmed/34794450
http://dx.doi.org/10.1186/s12931-021-01889-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603488/
https://www.ncbi.nlm.nih.gov/pubmed/34794450
http://dx.doi.org/10.1186/s12931-021-01889-4

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