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Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series
BACKGROUND: Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still unknown...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603560/ https://www.ncbi.nlm.nih.gov/pubmed/34794441 http://dx.doi.org/10.1186/s12917-021-03066-7 |
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author | Nunes Rodrigues, Tania C. Vandenabeele, Sophie I. |
author_facet | Nunes Rodrigues, Tania C. Vandenabeele, Sophie I. |
author_sort | Nunes Rodrigues, Tania C. |
collection | PubMed |
description | BACKGROUND: Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still unknown, and no association has been demonstrated with SMO. We compared Malassezia IgE levels, intradermal test and histology changes in SMO dogs with the more conventional Malassezia otitis (MO) presentation. RESULTS: Three dogs (case 1, case 2 and case 3) were diagnosed with SMO, one dog (case 4) was diagnosed with unilateral MO and unilateral SMO, and one dog (case 5) was diagnosed with MO. Only one case (case 4) with SMO/MO had a positive Intradermal Allergy Test (IDAT) and elevated IgE levels for Malassezia. Histopathology findings from SMO revealed: interface dermatitis (case 1 and 3), lymphocytic dermatitis (case 2) and chronic hyperplastic eosinophilic and lymphoplasmacytic dermatitis (case 4). Histopathology findings from MO showed perivascular dermatitis (case 4 and 5). All the cases were treated successfully. CONCLUSIONS: SMO presents with a distinct clinical phenotype in comparison with conventional MO. No consistent aetiology could be isolated. In these clinical cases it is possible that previous treatments could have influenced the results. More research is needed to understand the possible aetiologies and the pathogenesis of SMO. |
format | Online Article Text |
id | pubmed-8603560 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-86035602021-11-19 Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series Nunes Rodrigues, Tania C. Vandenabeele, Sophie I. BMC Vet Res Research BACKGROUND: Rarely, Malassezia otitis presents as a painful, erosive otitis with an otic discharge containing Malassezia and neutrophils on cytology. There are no published reports of this type of suppurative Malassezia otitis (SMO). The role of Malassezia hypersensitivity in otitis is still unknown, and no association has been demonstrated with SMO. We compared Malassezia IgE levels, intradermal test and histology changes in SMO dogs with the more conventional Malassezia otitis (MO) presentation. RESULTS: Three dogs (case 1, case 2 and case 3) were diagnosed with SMO, one dog (case 4) was diagnosed with unilateral MO and unilateral SMO, and one dog (case 5) was diagnosed with MO. Only one case (case 4) with SMO/MO had a positive Intradermal Allergy Test (IDAT) and elevated IgE levels for Malassezia. Histopathology findings from SMO revealed: interface dermatitis (case 1 and 3), lymphocytic dermatitis (case 2) and chronic hyperplastic eosinophilic and lymphoplasmacytic dermatitis (case 4). Histopathology findings from MO showed perivascular dermatitis (case 4 and 5). All the cases were treated successfully. CONCLUSIONS: SMO presents with a distinct clinical phenotype in comparison with conventional MO. No consistent aetiology could be isolated. In these clinical cases it is possible that previous treatments could have influenced the results. More research is needed to understand the possible aetiologies and the pathogenesis of SMO. BioMed Central 2021-11-18 /pmc/articles/PMC8603560/ /pubmed/34794441 http://dx.doi.org/10.1186/s12917-021-03066-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Nunes Rodrigues, Tania C. Vandenabeele, Sophie I. Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
title | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
title_full | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
title_fullStr | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
title_full_unstemmed | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
title_short | Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series |
title_sort | pilot study of dogs with suppurative and non-suppurative malassezia otitis: a case series |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603560/ https://www.ncbi.nlm.nih.gov/pubmed/34794441 http://dx.doi.org/10.1186/s12917-021-03066-7 |
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