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Fibroblast growth factor 7 releasing particles enhance islet engraftment and improve metabolic control following islet transplantation in mice with diabetes

Transplantation of islets in type 1 diabetes (T1D) is limited by poor islet engraftment into the liver, with two to three donor pancreases required per recipient. We aimed to condition the liver to enhance islet engraftment to improve long‐term graft function. Diabetic mice received a non‐curative i...

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Detalles Bibliográficos
Autores principales: Alwahsh, Salamah M., Qutachi, Omar, Starkey Lewis, Philip J., Bond, Andrew, Noble, June, Burgoyne, Paul, Morton, Nik, Carter, Rod, Mann, Janet, Ferreira‐Gonzalez, Sofia, Alvarez‐Paino, Marta, Forbes, Stuart J., Shakesheff, Kevin M., Forbes, Shareen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603932/
https://www.ncbi.nlm.nih.gov/pubmed/33428803
http://dx.doi.org/10.1111/ajt.16488

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