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Fibroblast growth factor 7 releasing particles enhance islet engraftment and improve metabolic control following islet transplantation in mice with diabetes
Transplantation of islets in type 1 diabetes (T1D) is limited by poor islet engraftment into the liver, with two to three donor pancreases required per recipient. We aimed to condition the liver to enhance islet engraftment to improve long‐term graft function. Diabetic mice received a non‐curative i...
Autores principales: | Alwahsh, Salamah M., Qutachi, Omar, Starkey Lewis, Philip J., Bond, Andrew, Noble, June, Burgoyne, Paul, Morton, Nik, Carter, Rod, Mann, Janet, Ferreira‐Gonzalez, Sofia, Alvarez‐Paino, Marta, Forbes, Stuart J., Shakesheff, Kevin M., Forbes, Shareen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603932/ https://www.ncbi.nlm.nih.gov/pubmed/33428803 http://dx.doi.org/10.1111/ajt.16488 |
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