Defective Toll-Like Receptors Driven B Cell Response in Hyper IgE Syndrome Patients With STAT3 Mutations

Autosomal dominant hyper-IgE syndrome (AD-HIES) is a rare inherited primary immunodeficient disease (PIDs), which is caused by STAT3 gene mutations. Previous studies indicated a defective Toll-like receptor (TLR) 9-induced B cell response in AD-HIES patients, including proliferation, and IgG product...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Ruolan, Wu, Jing, Jin, Yingying, Chen, Tongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604043/
https://www.ncbi.nlm.nih.gov/pubmed/34805040
http://dx.doi.org/10.3389/fped.2021.738799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604043/
https://www.ncbi.nlm.nih.gov/pubmed/34805040
http://dx.doi.org/10.3389/fped.2021.738799

Ejemplares similares