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QSDB—a graphical Quorum Sensing Database

The human microbiome is largely shaped by the chemical interactions of its microbial members, which includes cross-talk via shared signals or quenching of the signalling of other species. Quorum sensing is a process that allows microbes to coordinate their behaviour in dependence of their population...

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Detalles Bibliográficos
Autores principales: Klein, Karsten, Garkov, Dimitar, Rütschlin, Sina, Böttcher, Thomas, Schreiber, Falk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604260/
https://www.ncbi.nlm.nih.gov/pubmed/34559210
http://dx.doi.org/10.1093/database/baab058
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author Klein, Karsten
Garkov, Dimitar
Rütschlin, Sina
Böttcher, Thomas
Schreiber, Falk
author_facet Klein, Karsten
Garkov, Dimitar
Rütschlin, Sina
Böttcher, Thomas
Schreiber, Falk
author_sort Klein, Karsten
collection PubMed
description The human microbiome is largely shaped by the chemical interactions of its microbial members, which includes cross-talk via shared signals or quenching of the signalling of other species. Quorum sensing is a process that allows microbes to coordinate their behaviour in dependence of their population density and to adjust gene expression accordingly. We present the Quorum Sensing Database (QSDB), a comprehensive database of all published sensing and quenching relations between organisms and signalling molecules of the human microbiome, as well as an interactive web interface that allows browsing the database, provides graphical depictions of sensing mechanisms as Systems Biology Graphical Notation diagrams and links to other databases. Database URL: QSDB (Quorum Sensing DataBase) is freely available via an interactive web interface and as a downloadable csv file at http://qsdb.org.
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spelling pubmed-86042602021-11-22 QSDB—a graphical Quorum Sensing Database Klein, Karsten Garkov, Dimitar Rütschlin, Sina Böttcher, Thomas Schreiber, Falk Database (Oxford) Database Tool The human microbiome is largely shaped by the chemical interactions of its microbial members, which includes cross-talk via shared signals or quenching of the signalling of other species. Quorum sensing is a process that allows microbes to coordinate their behaviour in dependence of their population density and to adjust gene expression accordingly. We present the Quorum Sensing Database (QSDB), a comprehensive database of all published sensing and quenching relations between organisms and signalling molecules of the human microbiome, as well as an interactive web interface that allows browsing the database, provides graphical depictions of sensing mechanisms as Systems Biology Graphical Notation diagrams and links to other databases. Database URL: QSDB (Quorum Sensing DataBase) is freely available via an interactive web interface and as a downloadable csv file at http://qsdb.org. Oxford University Press 2021-11-26 /pmc/articles/PMC8604260/ /pubmed/34559210 http://dx.doi.org/10.1093/database/baab058 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Tool
Klein, Karsten
Garkov, Dimitar
Rütschlin, Sina
Böttcher, Thomas
Schreiber, Falk
QSDB—a graphical Quorum Sensing Database
title QSDB—a graphical Quorum Sensing Database
title_full QSDB—a graphical Quorum Sensing Database
title_fullStr QSDB—a graphical Quorum Sensing Database
title_full_unstemmed QSDB—a graphical Quorum Sensing Database
title_short QSDB—a graphical Quorum Sensing Database
title_sort qsdb—a graphical quorum sensing database
topic Database Tool
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604260/
https://www.ncbi.nlm.nih.gov/pubmed/34559210
http://dx.doi.org/10.1093/database/baab058
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