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QSDB—a graphical Quorum Sensing Database
The human microbiome is largely shaped by the chemical interactions of its microbial members, which includes cross-talk via shared signals or quenching of the signalling of other species. Quorum sensing is a process that allows microbes to coordinate their behaviour in dependence of their population...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604260/ https://www.ncbi.nlm.nih.gov/pubmed/34559210 http://dx.doi.org/10.1093/database/baab058 |
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author | Klein, Karsten Garkov, Dimitar Rütschlin, Sina Böttcher, Thomas Schreiber, Falk |
author_facet | Klein, Karsten Garkov, Dimitar Rütschlin, Sina Böttcher, Thomas Schreiber, Falk |
author_sort | Klein, Karsten |
collection | PubMed |
description | The human microbiome is largely shaped by the chemical interactions of its microbial members, which includes cross-talk via shared signals or quenching of the signalling of other species. Quorum sensing is a process that allows microbes to coordinate their behaviour in dependence of their population density and to adjust gene expression accordingly. We present the Quorum Sensing Database (QSDB), a comprehensive database of all published sensing and quenching relations between organisms and signalling molecules of the human microbiome, as well as an interactive web interface that allows browsing the database, provides graphical depictions of sensing mechanisms as Systems Biology Graphical Notation diagrams and links to other databases. Database URL: QSDB (Quorum Sensing DataBase) is freely available via an interactive web interface and as a downloadable csv file at http://qsdb.org. |
format | Online Article Text |
id | pubmed-8604260 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-86042602021-11-22 QSDB—a graphical Quorum Sensing Database Klein, Karsten Garkov, Dimitar Rütschlin, Sina Böttcher, Thomas Schreiber, Falk Database (Oxford) Database Tool The human microbiome is largely shaped by the chemical interactions of its microbial members, which includes cross-talk via shared signals or quenching of the signalling of other species. Quorum sensing is a process that allows microbes to coordinate their behaviour in dependence of their population density and to adjust gene expression accordingly. We present the Quorum Sensing Database (QSDB), a comprehensive database of all published sensing and quenching relations between organisms and signalling molecules of the human microbiome, as well as an interactive web interface that allows browsing the database, provides graphical depictions of sensing mechanisms as Systems Biology Graphical Notation diagrams and links to other databases. Database URL: QSDB (Quorum Sensing DataBase) is freely available via an interactive web interface and as a downloadable csv file at http://qsdb.org. Oxford University Press 2021-11-26 /pmc/articles/PMC8604260/ /pubmed/34559210 http://dx.doi.org/10.1093/database/baab058 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Database Tool Klein, Karsten Garkov, Dimitar Rütschlin, Sina Böttcher, Thomas Schreiber, Falk QSDB—a graphical Quorum Sensing Database |
title | QSDB—a graphical Quorum Sensing Database |
title_full | QSDB—a graphical Quorum Sensing Database |
title_fullStr | QSDB—a graphical Quorum Sensing Database |
title_full_unstemmed | QSDB—a graphical Quorum Sensing Database |
title_short | QSDB—a graphical Quorum Sensing Database |
title_sort | qsdb—a graphical quorum sensing database |
topic | Database Tool |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604260/ https://www.ncbi.nlm.nih.gov/pubmed/34559210 http://dx.doi.org/10.1093/database/baab058 |
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