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Size of HIV‐1 reservoir is associated with telomere shortening and immunosenescence in early‐treated European children with perinatally acquired HIV‐1

INTRODUCTION: Persistence of HIV‐1, causing chronic immune activation, is a key determinant of premature senescence. Early antiretroviral therapy (ART) has been associated with a reduced HIV‐1 reservoir in children with perinatally acquired HIV‐1 (PHIV), but its impact on the senescence process is a...

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Detalles Bibliográficos
Autores principales: Dalzini, Annalisa, Ballin, Giovanni, Dominguez‐Rodriguez, Sara, Rojo, Pablo, Petrara, Maria Raffaella, Foster, Caroline, Cotugno, Nicola, Ruggiero, Alessandra, Nastouli, Eleni, Klein, Nigel, Rinaldi, Stefano, Pahwa, Savita, Rossi, Paolo, Giaquinto, Carlo, Palma, Paolo, De Rossi, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604380/
https://www.ncbi.nlm.nih.gov/pubmed/34797948
http://dx.doi.org/10.1002/jia2.25847