An efficient system for bioconjugation based on a widely applicable engineered O-glycosylation tag: Short title: Controlled bioconjugation via O-glycan engineering

Bioconjugates are an important class of therapeutic molecules. To date, O-glycan-based metabolic glycoengineering has had limited use in this field, due to the complexities of the endogenous O-glycosylation pathway and the lack of an O-glycosylation consensus sequence. Here, we describe the developm...

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Detalles Bibliográficos
Autores principales: Murray, Thomas V., Kozakowska-McDonnell, Kasia, Tibbles, Adam, Taylor, Annabel, Higazi, Daniel, Rossy, Emmanuel, Rossi, Alessandra, Genapathy, Sivaneswary, Tamburrino, Giulia, Rath, Nicola, Tigue, Natalie, Lindo, Vivian, Vaughan, Tristan, Papworth, Monika A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604393/
https://www.ncbi.nlm.nih.gov/pubmed/34781832
http://dx.doi.org/10.1080/19420862.2021.1992068

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