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SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?

Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggeste...

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Detalles Bibliográficos
Autores principales: Muhammad, Jibran Sualeh, Siddiqui, Ruqaiyyah, Khan, Naveed Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604571/
https://www.ncbi.nlm.nih.gov/pubmed/34823125
http://dx.doi.org/10.1016/j.compbiolchem.2021.107602
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author Muhammad, Jibran Sualeh
Siddiqui, Ruqaiyyah
Khan, Naveed Ahmed
author_facet Muhammad, Jibran Sualeh
Siddiqui, Ruqaiyyah
Khan, Naveed Ahmed
author_sort Muhammad, Jibran Sualeh
collection PubMed
description Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggested that inhibition of CCR2, DPP9, HSPA1L, IFNAR2, OAS1, and TYK2 may, in part, explain UVB-mediated protection against severe consequences of COVID-19.
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spelling pubmed-86045712021-11-22 SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19? Muhammad, Jibran Sualeh Siddiqui, Ruqaiyyah Khan, Naveed Ahmed Comput Biol Chem Article Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggested that inhibition of CCR2, DPP9, HSPA1L, IFNAR2, OAS1, and TYK2 may, in part, explain UVB-mediated protection against severe consequences of COVID-19. Elsevier Ltd. 2022-02 2021-11-20 /pmc/articles/PMC8604571/ /pubmed/34823125 http://dx.doi.org/10.1016/j.compbiolchem.2021.107602 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Muhammad, Jibran Sualeh
Siddiqui, Ruqaiyyah
Khan, Naveed Ahmed
SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?
title SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?
title_full SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?
title_fullStr SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?
title_full_unstemmed SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?
title_short SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?
title_sort sars-cov-2: can sunlight exposure reduce the risk of developing severe consequences of covid-19?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604571/
https://www.ncbi.nlm.nih.gov/pubmed/34823125
http://dx.doi.org/10.1016/j.compbiolchem.2021.107602
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