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Activation of GPR18 by Resolvin D2 Relieves Pain and Improves Bladder Function in Cyclophosphamide-Induced Cystitis Through Inhibiting TRPV1

PURPOSE: Hyperalgesia and bladder overactivity are two main symptoms of interstitial cystitis/bladder pain syndrome (IC/BPS). Cannabinoid receptors participate in the modulation of pain and bladder function. GPR18, a member of the cannabinoid receptor family, also participates in the regulation of p...

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Detalles Bibliográficos
Autores principales: Lu, Qudong, Yang, Yang, Zhang, Hengshuai, Chen, Cheng, Zhao, Jiang, Yang, Zhenxing, Fan, Yi, Li, Longkun, Feng, Huan, Zhu, Jingzhen, Yi, Shanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604640/
https://www.ncbi.nlm.nih.gov/pubmed/34815664
http://dx.doi.org/10.2147/DDDT.S329507