Cargando…
A fractional-order multi-vaccination model for COVID-19 with non-singular kernel
This work examines the impact of multiple vaccination strategies on the dynamics of COVID-19 in a population using the Atangana-Baleanu derivative. The existence and uniqueness of solution of the model is proven using Banach’s fixed point theorem. Local and global asymptotic stability of the equilib...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604708/ http://dx.doi.org/10.1016/j.aej.2021.11.037 |
_version_ | 1784602020681875456 |
---|---|
author | Omame, A. Okuonghae, D. Nwajeri, Ugochukwu K. Onyenegecha, Chibueze P. |
author_facet | Omame, A. Okuonghae, D. Nwajeri, Ugochukwu K. Onyenegecha, Chibueze P. |
author_sort | Omame, A. |
collection | PubMed |
description | This work examines the impact of multiple vaccination strategies on the dynamics of COVID-19 in a population using the Atangana-Baleanu derivative. The existence and uniqueness of solution of the model is proven using Banach’s fixed point theorem. Local and global asymptotic stability of the equilibria of the model is also proven (under some conditions). Conditions for the existence of a unique or multiple equilibria are also derived and the model is shown to undergo backward bifurcation under certain scenarios. Using available data for the Pfizer, Moderna and Janssen vaccination programme for the city of Texas, United States of America from March 13, 2021 to June 29, 2021, the model is fitted using the three data sets. The three vaccination rates [Formula: see text] and [Formula: see text] corresponding to each vaccine as well as the effective contact rate for COVID-19 transmission, [Formula: see text] , are estimated. Simulations of the model under different vaccination strategies are carried out. The results show that the three vaccination strategies not only cause significant reduction in the new asymptomatic and vaccinated symptomatic cases but also cause great decrease in the total number of vaccinated symptomatic individuals with severe COVID-19 illness. |
format | Online Article Text |
id | pubmed-8604708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86047082021-11-22 A fractional-order multi-vaccination model for COVID-19 with non-singular kernel Omame, A. Okuonghae, D. Nwajeri, Ugochukwu K. Onyenegecha, Chibueze P. Alexandria Engineering Journal Article This work examines the impact of multiple vaccination strategies on the dynamics of COVID-19 in a population using the Atangana-Baleanu derivative. The existence and uniqueness of solution of the model is proven using Banach’s fixed point theorem. Local and global asymptotic stability of the equilibria of the model is also proven (under some conditions). Conditions for the existence of a unique or multiple equilibria are also derived and the model is shown to undergo backward bifurcation under certain scenarios. Using available data for the Pfizer, Moderna and Janssen vaccination programme for the city of Texas, United States of America from March 13, 2021 to June 29, 2021, the model is fitted using the three data sets. The three vaccination rates [Formula: see text] and [Formula: see text] corresponding to each vaccine as well as the effective contact rate for COVID-19 transmission, [Formula: see text] , are estimated. Simulations of the model under different vaccination strategies are carried out. The results show that the three vaccination strategies not only cause significant reduction in the new asymptomatic and vaccinated symptomatic cases but also cause great decrease in the total number of vaccinated symptomatic individuals with severe COVID-19 illness. THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. 2022-08 2021-11-20 /pmc/articles/PMC8604708/ http://dx.doi.org/10.1016/j.aej.2021.11.037 Text en © 2021 THE AUTHORS Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Omame, A. Okuonghae, D. Nwajeri, Ugochukwu K. Onyenegecha, Chibueze P. A fractional-order multi-vaccination model for COVID-19 with non-singular kernel |
title | A fractional-order multi-vaccination model for COVID-19 with non-singular kernel |
title_full | A fractional-order multi-vaccination model for COVID-19 with non-singular kernel |
title_fullStr | A fractional-order multi-vaccination model for COVID-19 with non-singular kernel |
title_full_unstemmed | A fractional-order multi-vaccination model for COVID-19 with non-singular kernel |
title_short | A fractional-order multi-vaccination model for COVID-19 with non-singular kernel |
title_sort | fractional-order multi-vaccination model for covid-19 with non-singular kernel |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604708/ http://dx.doi.org/10.1016/j.aej.2021.11.037 |
work_keys_str_mv | AT omamea afractionalordermultivaccinationmodelforcovid19withnonsingularkernel AT okuonghaed afractionalordermultivaccinationmodelforcovid19withnonsingularkernel AT nwajeriugochukwuk afractionalordermultivaccinationmodelforcovid19withnonsingularkernel AT onyenegechachibuezep afractionalordermultivaccinationmodelforcovid19withnonsingularkernel AT omamea fractionalordermultivaccinationmodelforcovid19withnonsingularkernel AT okuonghaed fractionalordermultivaccinationmodelforcovid19withnonsingularkernel AT nwajeriugochukwuk fractionalordermultivaccinationmodelforcovid19withnonsingularkernel AT onyenegechachibuezep fractionalordermultivaccinationmodelforcovid19withnonsingularkernel |