Cargando…

The use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn

BACKGROUND: Although Transient tachypnea of the newborn (TTN) is one of the most common causes of respiratory distress in the newborn period, there is no laboratory parameter used to diagnose it. Immatur granulocyte (IG) measurement is accepted as a useful indicator that can be used in early detecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Çiğri, Emrah, Gülten, Sedat, Yildiz, Eren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604747/
https://www.ncbi.nlm.nih.gov/pubmed/34824833
http://dx.doi.org/10.1016/j.amsu.2021.102960
_version_ 1784602030153662464
author Çiğri, Emrah
Gülten, Sedat
Yildiz, Eren
author_facet Çiğri, Emrah
Gülten, Sedat
Yildiz, Eren
author_sort Çiğri, Emrah
collection PubMed
description BACKGROUND: Although Transient tachypnea of the newborn (TTN) is one of the most common causes of respiratory distress in the newborn period, there is no laboratory parameter used to diagnose it. Immatur granulocyte (IG) measurement is accepted as a useful indicator that can be used in early detection of many infectious conditions, especially neonatal sepsis. In this study, it was aimed to determine if IG and other complete blood count (CBC) parameters could be used as laboratory findings supporting TTN diagnosis. MATERIALS AND METHODS: This study, which was retrospectively planned, was conducted in the neonatal intensive care unit (NICU) a public hospital between January 1, 2019 and January 31, 2021. Randomly selected 50 infants, hospitalized with the diagnosis of TTN, constituted the patient group of the study. 50 infants hospitalized with the diagnosis of hyperbilirubinemia and did not have any additional problems accepted as the control group. IG and other CBC parameters of infants in the patient and control groups were compared in the study. RESULTS: There was no significant difference between the patient and control groups in terms of demographic data and types of delivery (p > 0.05). The rate of delivery by elective cesarean section (C/S) was significantly higher than the rate of normal spontaneous vaginal (NSV) delivery in the patient group (p < 0.001). The IG number and percentage, WBC (white blood cell) count, RDW (red cell distribution width), number and percentage of NRBC (nucleated red blood cell), neutrophil and lymphocyte ratio, count and percentage of basophil and PLR (platelet/lymphocyte ratio) of the patient group was significantly higher than the control group (p < 0.05). CONCLUSION: According to the findings obtained in the study, it was concluded that IG and other CBC parameters may be used to support clinical and imaging findings to diagnose transient tachypnea of the newborn.
format Online
Article
Text
id pubmed-8604747
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-86047472021-11-24 The use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn Çiğri, Emrah Gülten, Sedat Yildiz, Eren Ann Med Surg (Lond) Health Economic Evaluation BACKGROUND: Although Transient tachypnea of the newborn (TTN) is one of the most common causes of respiratory distress in the newborn period, there is no laboratory parameter used to diagnose it. Immatur granulocyte (IG) measurement is accepted as a useful indicator that can be used in early detection of many infectious conditions, especially neonatal sepsis. In this study, it was aimed to determine if IG and other complete blood count (CBC) parameters could be used as laboratory findings supporting TTN diagnosis. MATERIALS AND METHODS: This study, which was retrospectively planned, was conducted in the neonatal intensive care unit (NICU) a public hospital between January 1, 2019 and January 31, 2021. Randomly selected 50 infants, hospitalized with the diagnosis of TTN, constituted the patient group of the study. 50 infants hospitalized with the diagnosis of hyperbilirubinemia and did not have any additional problems accepted as the control group. IG and other CBC parameters of infants in the patient and control groups were compared in the study. RESULTS: There was no significant difference between the patient and control groups in terms of demographic data and types of delivery (p > 0.05). The rate of delivery by elective cesarean section (C/S) was significantly higher than the rate of normal spontaneous vaginal (NSV) delivery in the patient group (p < 0.001). The IG number and percentage, WBC (white blood cell) count, RDW (red cell distribution width), number and percentage of NRBC (nucleated red blood cell), neutrophil and lymphocyte ratio, count and percentage of basophil and PLR (platelet/lymphocyte ratio) of the patient group was significantly higher than the control group (p < 0.05). CONCLUSION: According to the findings obtained in the study, it was concluded that IG and other CBC parameters may be used to support clinical and imaging findings to diagnose transient tachypnea of the newborn. Elsevier 2021-10-22 /pmc/articles/PMC8604747/ /pubmed/34824833 http://dx.doi.org/10.1016/j.amsu.2021.102960 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Health Economic Evaluation
Çiğri, Emrah
Gülten, Sedat
Yildiz, Eren
The use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn
title The use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn
title_full The use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn
title_fullStr The use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn
title_full_unstemmed The use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn
title_short The use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn
title_sort use of immature granulocyte and other complete blood count parameters in the diagnosis of transient tachypnea of the newborn
topic Health Economic Evaluation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604747/
https://www.ncbi.nlm.nih.gov/pubmed/34824833
http://dx.doi.org/10.1016/j.amsu.2021.102960
work_keys_str_mv AT cigriemrah theuseofimmaturegranulocyteandothercompletebloodcountparametersinthediagnosisoftransienttachypneaofthenewborn
AT gultensedat theuseofimmaturegranulocyteandothercompletebloodcountparametersinthediagnosisoftransienttachypneaofthenewborn
AT yildizeren theuseofimmaturegranulocyteandothercompletebloodcountparametersinthediagnosisoftransienttachypneaofthenewborn
AT cigriemrah useofimmaturegranulocyteandothercompletebloodcountparametersinthediagnosisoftransienttachypneaofthenewborn
AT gultensedat useofimmaturegranulocyteandothercompletebloodcountparametersinthediagnosisoftransienttachypneaofthenewborn
AT yildizeren useofimmaturegranulocyteandothercompletebloodcountparametersinthediagnosisoftransienttachypneaofthenewborn