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Macrophage polarization state affects lipid composition and the channeling of exogenous fatty acids into endogenous lipid pools
Adipose-tissue-resident macrophages (ATMs) maintain metabolic homeostasis but also contribute to obesity-induced adipose tissue inflammation and metabolic dysfunction. Central to these contrasting effects of ATMs on metabolic homeostasis is the interaction of macrophages with fatty acids. Fatty acid...
Autores principales: | Morgan, Pooranee K., Huynh, Kevin, Pernes, Gerard, Miotto, Paula M., Mellett, Natalie A., Giles, Corey, Meikle, Peter J., Murphy, Andrew J., Lancaster, Graeme I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604758/ https://www.ncbi.nlm.nih.gov/pubmed/34695418 http://dx.doi.org/10.1016/j.jbc.2021.101341 |
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