Integrated Systems Analysis of the Murine and Human Pancreatic Cancer Glycomes Reveals a Tumor-Promoting Role for ST6GAL1

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the United States. Glycans, such as carbohydrate antigen 19-9, are biomarkers of PDAC and are emerging as important modulators of cancer phenotypes. Herein, we used a systems-based approach integrating glycomic ana...

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Detalles Bibliográficos
Autores principales: Kurz, Emma, Chen, Shuhui, Vucic, Emily, Baptiste, Gillian, Loomis, Cynthia, Agrawal, Praveen, Hajdu, Cristina, Bar-Sagi, Dafna, Mahal, Lara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604807/
https://www.ncbi.nlm.nih.gov/pubmed/34634466
http://dx.doi.org/10.1016/j.mcpro.2021.100160

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