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Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users

PURPOSE: Purpose of this study is to evaluate plan quality on the MRIdian (Viewray Inc., Oakwood Village, OH, USA) system for head and neck cancer (HNC) through comparison of planning approaches of several centers. METHODS: A total of 14 planners using the MRIdian planning system participated in thi...

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Autores principales: Chamberlain, Madalyne, Krayenbuehl, Jerome, van Timmeren, Janita E., Wilke, Lotte, Andratschke, Nicolaus, Garcia Schüler, Helena, Tanadini-Lang, Stephanie, Guckenberger, Matthias, Balermpas, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604891/
https://www.ncbi.nlm.nih.gov/pubmed/33891126
http://dx.doi.org/10.1007/s00066-021-01771-8
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author Chamberlain, Madalyne
Krayenbuehl, Jerome
van Timmeren, Janita E.
Wilke, Lotte
Andratschke, Nicolaus
Garcia Schüler, Helena
Tanadini-Lang, Stephanie
Guckenberger, Matthias
Balermpas, Panagiotis
author_facet Chamberlain, Madalyne
Krayenbuehl, Jerome
van Timmeren, Janita E.
Wilke, Lotte
Andratschke, Nicolaus
Garcia Schüler, Helena
Tanadini-Lang, Stephanie
Guckenberger, Matthias
Balermpas, Panagiotis
author_sort Chamberlain, Madalyne
collection PubMed
description PURPOSE: Purpose of this study is to evaluate plan quality on the MRIdian (Viewray Inc., Oakwood Village, OH, USA) system for head and neck cancer (HNC) through comparison of planning approaches of several centers. METHODS: A total of 14 planners using the MRIdian planning system participated in this treatment challenge, centrally organized by ViewRay, for one contoured case of oropharyngeal carcinoma with standard constraints for organs at risk (OAR). Homogeneity, conformity, sparing of OARs, and other parameters were evaluated according to The International Commission on Radiation Units and Measurements (ICRU) recommendations anonymously, and then compared between centers. Differences amongst centers were assessed by means of Wilcoxon test. Each plan had to fulfil hard constraints based on dose–volume histogram (DVH) parameters and delivery time. A plan quality metric (PQM) was evaluated. The PQM was defined as the sum of 16 submetrics characterizing different DVH goals. RESULTS: For most dose parameters the median score of all centers was higher than the threshold that results in an ideal score. Six participants achieved the maximum number of points for the OAR dose parameters, and none had an unacceptable performance on any of the metrics. Each planner was able to achieve all the requirements except for one which exceeded delivery time. The number of segments correlated to improved PQM and inversely correlated to brainstem D(0.1cc) and to Planning Target Volume1 (PTV) D(0.1cc). Total planning experience inversely correlated to spinal canal dose. CONCLUSION: Magnetic Resonance Image (MRI) linac-based planning for HNC is already feasible with good quality. Generally, an increased number of segments and increasing planning experience are able to provide better results regarding planning quality without significantly prolonging overall treatment time. SUPPLEMENTARY INFORMATION: The online version of this article (10.1007/s00066-021-01771-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-86048912021-12-03 Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users Chamberlain, Madalyne Krayenbuehl, Jerome van Timmeren, Janita E. Wilke, Lotte Andratschke, Nicolaus Garcia Schüler, Helena Tanadini-Lang, Stephanie Guckenberger, Matthias Balermpas, Panagiotis Strahlenther Onkol Original Article PURPOSE: Purpose of this study is to evaluate plan quality on the MRIdian (Viewray Inc., Oakwood Village, OH, USA) system for head and neck cancer (HNC) through comparison of planning approaches of several centers. METHODS: A total of 14 planners using the MRIdian planning system participated in this treatment challenge, centrally organized by ViewRay, for one contoured case of oropharyngeal carcinoma with standard constraints for organs at risk (OAR). Homogeneity, conformity, sparing of OARs, and other parameters were evaluated according to The International Commission on Radiation Units and Measurements (ICRU) recommendations anonymously, and then compared between centers. Differences amongst centers were assessed by means of Wilcoxon test. Each plan had to fulfil hard constraints based on dose–volume histogram (DVH) parameters and delivery time. A plan quality metric (PQM) was evaluated. The PQM was defined as the sum of 16 submetrics characterizing different DVH goals. RESULTS: For most dose parameters the median score of all centers was higher than the threshold that results in an ideal score. Six participants achieved the maximum number of points for the OAR dose parameters, and none had an unacceptable performance on any of the metrics. Each planner was able to achieve all the requirements except for one which exceeded delivery time. The number of segments correlated to improved PQM and inversely correlated to brainstem D(0.1cc) and to Planning Target Volume1 (PTV) D(0.1cc). Total planning experience inversely correlated to spinal canal dose. CONCLUSION: Magnetic Resonance Image (MRI) linac-based planning for HNC is already feasible with good quality. Generally, an increased number of segments and increasing planning experience are able to provide better results regarding planning quality without significantly prolonging overall treatment time. SUPPLEMENTARY INFORMATION: The online version of this article (10.1007/s00066-021-01771-8) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2021-04-23 2021 /pmc/articles/PMC8604891/ /pubmed/33891126 http://dx.doi.org/10.1007/s00066-021-01771-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Chamberlain, Madalyne
Krayenbuehl, Jerome
van Timmeren, Janita E.
Wilke, Lotte
Andratschke, Nicolaus
Garcia Schüler, Helena
Tanadini-Lang, Stephanie
Guckenberger, Matthias
Balermpas, Panagiotis
Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users
title Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users
title_full Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users
title_fullStr Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users
title_full_unstemmed Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users
title_short Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users
title_sort head and neck radiotherapy on the mr linac: a multicenter planning challenge amongst mridian platform users
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604891/
https://www.ncbi.nlm.nih.gov/pubmed/33891126
http://dx.doi.org/10.1007/s00066-021-01771-8
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