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Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biology
Telomere maintenance and tumor cell differentiation have been separately implicated in neuroblastoma malignancy. Their mechanistic connection is unclear. We analyzed neuroblastoma cell lines and morphologic subclones representing the adrenergic (ADRN) and mesenchymal (MES) differentiation states and...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604896/ https://www.ncbi.nlm.nih.gov/pubmed/34799676 http://dx.doi.org/10.1038/s42003-021-02821-8 |