Cuprizone feed formulation influences the extent of demyelinating disease pathology

Cuprizone is a copper-chelating agent that induces pathology similar to that within some multiple sclerosis (MS) lesions. The reliability and reproducibility of cuprizone for inducing demyelinating disease pathology depends on the animals ingesting consistent doses of cuprizone. Cuprizone-containing...

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Detalles Bibliográficos
Autores principales: Toomey, Lillian M., Papini, Melissa, Lins, Brittney, Wright, Alexander J., Warnock, Andrew, McGonigle, Terence, Hellewell, Sarah C., Bartlett, Carole A., Anyaegbu, Chidozie, Fitzgerald, Melinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604913/
https://www.ncbi.nlm.nih.gov/pubmed/34799634
http://dx.doi.org/10.1038/s41598-021-01963-3

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