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Seasonal diets supersede host species in shaping the distal gut microbiota of Yaks and Tibetan sheep

Yaks and Tibetan sheep are important and renowned livestock of the Qinghai-Tibetan Plateau (QTP). Both host genetics and environmental factors can shape the composition of gut microbiota, however, there is still no consensus on which is the more dominant factor. To investigate the influence of hosts...

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Autores principales: Wei, Xiaojuan, Dong, Zhen, Cheng, Fusheng, Shi, Hongmei, Zhou, Xuzheng, Li, Bing, Wang, Ling, Wang, Weiwei, Zhang, Jiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604981/
https://www.ncbi.nlm.nih.gov/pubmed/34799677
http://dx.doi.org/10.1038/s41598-021-99351-4
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author Wei, Xiaojuan
Dong, Zhen
Cheng, Fusheng
Shi, Hongmei
Zhou, Xuzheng
Li, Bing
Wang, Ling
Wang, Weiwei
Zhang, Jiyu
author_facet Wei, Xiaojuan
Dong, Zhen
Cheng, Fusheng
Shi, Hongmei
Zhou, Xuzheng
Li, Bing
Wang, Ling
Wang, Weiwei
Zhang, Jiyu
author_sort Wei, Xiaojuan
collection PubMed
description Yaks and Tibetan sheep are important and renowned livestock of the Qinghai-Tibetan Plateau (QTP). Both host genetics and environmental factors can shape the composition of gut microbiota, however, there is still no consensus on which is the more dominant factor. To investigate the influence of hosts and seasons on the gut microbiome diversity component, we collected fecal samples from yaks and Tibetan sheep across different seasons (summer and winter), during which they consumed different diets. Using 16S rRNA sequencing, principal component analysis (PCoA) data showed that PCo1 explained 57.4% of the observed variance (P = 0.001) and clearly divided winter samples from summer ones, while PCo2 explained 7.1% of observed variance (P = 0.001) and mainly highlighted differences in host species. Cluster analysis data revealed that the gut microbiota composition displayed a convergence caused by season and not by genetics. Further, we profiled the gut microbial community and found that the more dominant genera in yak and Tibetan sheep microbiota were influenced by seasonal diets factors rather than genetics. This study therefore indicated that seasonal diet can trump host genetics even at higher taxonomic levels, thus providing a cautionary note for the breeding and management of these two species.
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spelling pubmed-86049812021-11-22 Seasonal diets supersede host species in shaping the distal gut microbiota of Yaks and Tibetan sheep Wei, Xiaojuan Dong, Zhen Cheng, Fusheng Shi, Hongmei Zhou, Xuzheng Li, Bing Wang, Ling Wang, Weiwei Zhang, Jiyu Sci Rep Article Yaks and Tibetan sheep are important and renowned livestock of the Qinghai-Tibetan Plateau (QTP). Both host genetics and environmental factors can shape the composition of gut microbiota, however, there is still no consensus on which is the more dominant factor. To investigate the influence of hosts and seasons on the gut microbiome diversity component, we collected fecal samples from yaks and Tibetan sheep across different seasons (summer and winter), during which they consumed different diets. Using 16S rRNA sequencing, principal component analysis (PCoA) data showed that PCo1 explained 57.4% of the observed variance (P = 0.001) and clearly divided winter samples from summer ones, while PCo2 explained 7.1% of observed variance (P = 0.001) and mainly highlighted differences in host species. Cluster analysis data revealed that the gut microbiota composition displayed a convergence caused by season and not by genetics. Further, we profiled the gut microbial community and found that the more dominant genera in yak and Tibetan sheep microbiota were influenced by seasonal diets factors rather than genetics. This study therefore indicated that seasonal diet can trump host genetics even at higher taxonomic levels, thus providing a cautionary note for the breeding and management of these two species. Nature Publishing Group UK 2021-11-19 /pmc/articles/PMC8604981/ /pubmed/34799677 http://dx.doi.org/10.1038/s41598-021-99351-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Wei, Xiaojuan
Dong, Zhen
Cheng, Fusheng
Shi, Hongmei
Zhou, Xuzheng
Li, Bing
Wang, Ling
Wang, Weiwei
Zhang, Jiyu
Seasonal diets supersede host species in shaping the distal gut microbiota of Yaks and Tibetan sheep
title Seasonal diets supersede host species in shaping the distal gut microbiota of Yaks and Tibetan sheep
title_full Seasonal diets supersede host species in shaping the distal gut microbiota of Yaks and Tibetan sheep
title_fullStr Seasonal diets supersede host species in shaping the distal gut microbiota of Yaks and Tibetan sheep
title_full_unstemmed Seasonal diets supersede host species in shaping the distal gut microbiota of Yaks and Tibetan sheep
title_short Seasonal diets supersede host species in shaping the distal gut microbiota of Yaks and Tibetan sheep
title_sort seasonal diets supersede host species in shaping the distal gut microbiota of yaks and tibetan sheep
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604981/
https://www.ncbi.nlm.nih.gov/pubmed/34799677
http://dx.doi.org/10.1038/s41598-021-99351-4
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