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BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities

Nicotinamide riboside (NR) is one of the orally bioavailable NAD(+) precursors and has been demonstrated to exhibit beneficial effects against aging and aging-associated diseases. However, the metabolic pathway of NR in vivo is not yet fully understood. Here, we demonstrate that orally administered...

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Detalles Bibliográficos
Autores principales:	Yaku, Keisuke, Palikhe, Sailesh, Izumi, Hironori, Yoshida, Tomoyuki, Hikosaka, Keisuke, Hayat, Faisal, Karim, Mariam, Iqbal, Tooba, Nitta, Yasuhito, Sato, Atsushi, Migaud, Marie E., Ishihara, Katsuhiko, Mori, Hisashi, Nakagawa, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604996/ https://www.ncbi.nlm.nih.gov/pubmed/34799586 http://dx.doi.org/10.1038/s41467-021-27080-3

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