Measurements of spontaneous CFTR-mediated ion transport without acute channel activation in airway epithelial cultures after modulator exposure

Quantitation of CFTR function in vitro is commonly performed by acutely stimulating then inhibiting ion transport through CFTR and measuring the resulting changes in transepithelial voltage (V(te)) and current (I(SC)). While this technique is suitable for measuring the maximum functional capacity of...

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Detalles Bibliográficos
Autores principales: Nick, Heidi J., Zeitlin, Pamela L., Yadav, Sangya, Bratcher, Preston E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605007/
https://www.ncbi.nlm.nih.gov/pubmed/34799640
http://dx.doi.org/10.1038/s41598-021-02044-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605007/
https://www.ncbi.nlm.nih.gov/pubmed/34799640
http://dx.doi.org/10.1038/s41598-021-02044-1

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