Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

Viral proteins make extensive use of short peptide interaction motifs to hijack cellular host factors. However, most current large-scale methods do not identify this important class of protein-protein interactions. Uncovering peptide mediated interactions provides both a molecular understanding of v...

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Detalles Bibliográficos
Autores principales: Kruse, Thomas, Benz, Caroline, Garvanska, Dimitriya H., Lindqvist, Richard, Mihalic, Filip, Coscia, Fabian, Inturi, Raviteja, Sayadi, Ahmed, Simonetti, Leandro, Nilsson, Emma, Ali, Muhammad, Kliche, Johanna, Moliner Morro, Ainhoa, Mund, Andreas, Andersson, Eva, McInerney, Gerald, Mann, Matthias, Jemth, Per, Davey, Norman E., Överby, Anna K., Nilsson, Jakob, Ivarsson, Ylva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605023/
https://www.ncbi.nlm.nih.gov/pubmed/34799561
http://dx.doi.org/10.1038/s41467-021-26498-z

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