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Functional solubilization of the β(2)-adrenoceptor using diisobutylene maleic acid

The β2-adrenoceptor (β2AR) is a well-established target in asthma and a prototypical G protein-coupled receptor for biophysical studies. Solubilization of membrane proteins has classically involved the use of detergents. However, the detergent environment differs from the native membrane environment...

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Detalles Bibliográficos
Autores principales:	Harwood, Clare.R., Sykes, David A., Hoare, Bradley L., Heydenreich, Franziska M., Uddin, Romez, Poyner, David R., Briddon, Stephen J., Veprintsev, D.B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605084/ https://www.ncbi.nlm.nih.gov/pubmed/34825145 http://dx.doi.org/10.1016/j.isci.2021.103362

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