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RUNX1/EGFR pathway contributes to STAT3 activation and tumor growth caused by hyperactivated mTORC1

Loss of function of tuberous sclerosis complex 1 or 2 (TSC1 or TSC2) leads to the activation of mammalian target of rapamycin complex 1 (mTORC1). Hyperactivated mTORC1 plays a critical role in tumor growth, but the underlying mechanism is still not completely elucidated. Here, by analyzing Tsc1- or...

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Detalles Bibliográficos
Autores principales:	Lin, Wei, Wan, Xiaofeng, Sun, Anjiang, Zhou, Meng, Chen, Xu, Li, Yanling, Wang, Zixi, Huang, Hailiang, Li, Hongwu, Chen, Xianguo, Hua, Juan, Zha, Xiaojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605091/ https://www.ncbi.nlm.nih.gov/pubmed/34853810 http://dx.doi.org/10.1016/j.omto.2021.10.009

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