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Shape-programmable artificial cilia for microfluidics

The artificial ciliary motion has been known not to be hydrodynamically optimal, limiting their associated applications in the microscale flow domain. One of the major hurdles of contemporary artificial cilia is its structural rigidity, which restricts their flexibility. To address this issue, this...

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Detalles Bibliográficos
Autores principales: Panigrahi, Bivas, Sahadevan, Vignesh, Chen, Chia-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605101/
https://www.ncbi.nlm.nih.gov/pubmed/34825146
http://dx.doi.org/10.1016/j.isci.2021.103367
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author Panigrahi, Bivas
Sahadevan, Vignesh
Chen, Chia-Yuan
author_facet Panigrahi, Bivas
Sahadevan, Vignesh
Chen, Chia-Yuan
author_sort Panigrahi, Bivas
collection PubMed
description The artificial ciliary motion has been known not to be hydrodynamically optimal, limiting their associated applications in the microscale flow domain. One of the major hurdles of contemporary artificial cilia is its structural rigidity, which restricts their flexibility. To address this issue, this work proposed a shape-programmable artificial cilia design with distinctive polydimethylsiloxane (PDMS) and magnetic segments distributed throughout the structure, which provided precise control for time-spatial modulation of the whole artificial cilia structure under external magnetic actuation. For the fabrication of the proposed multi-segment artificial cilia, a facile microfabrication process with stepwise mold blocking followed by the PDMS and magnetic composite casting was adopted. The hydrodynamic analysis further elucidated that the proposed artificial cilia beating induced significant flow disturbance within the flow field, and the associated application was demonstrated through an efficient mixing operation.
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spelling pubmed-86051012021-11-24 Shape-programmable artificial cilia for microfluidics Panigrahi, Bivas Sahadevan, Vignesh Chen, Chia-Yuan iScience Article The artificial ciliary motion has been known not to be hydrodynamically optimal, limiting their associated applications in the microscale flow domain. One of the major hurdles of contemporary artificial cilia is its structural rigidity, which restricts their flexibility. To address this issue, this work proposed a shape-programmable artificial cilia design with distinctive polydimethylsiloxane (PDMS) and magnetic segments distributed throughout the structure, which provided precise control for time-spatial modulation of the whole artificial cilia structure under external magnetic actuation. For the fabrication of the proposed multi-segment artificial cilia, a facile microfabrication process with stepwise mold blocking followed by the PDMS and magnetic composite casting was adopted. The hydrodynamic analysis further elucidated that the proposed artificial cilia beating induced significant flow disturbance within the flow field, and the associated application was demonstrated through an efficient mixing operation. Elsevier 2021-10-28 /pmc/articles/PMC8605101/ /pubmed/34825146 http://dx.doi.org/10.1016/j.isci.2021.103367 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Panigrahi, Bivas
Sahadevan, Vignesh
Chen, Chia-Yuan
Shape-programmable artificial cilia for microfluidics
title Shape-programmable artificial cilia for microfluidics
title_full Shape-programmable artificial cilia for microfluidics
title_fullStr Shape-programmable artificial cilia for microfluidics
title_full_unstemmed Shape-programmable artificial cilia for microfluidics
title_short Shape-programmable artificial cilia for microfluidics
title_sort shape-programmable artificial cilia for microfluidics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605101/
https://www.ncbi.nlm.nih.gov/pubmed/34825146
http://dx.doi.org/10.1016/j.isci.2021.103367
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AT chenchiayuan shapeprogrammableartificialciliaformicrofluidics