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Shape-programmable artificial cilia for microfluidics
The artificial ciliary motion has been known not to be hydrodynamically optimal, limiting their associated applications in the microscale flow domain. One of the major hurdles of contemporary artificial cilia is its structural rigidity, which restricts their flexibility. To address this issue, this...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605101/ https://www.ncbi.nlm.nih.gov/pubmed/34825146 http://dx.doi.org/10.1016/j.isci.2021.103367 |
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author | Panigrahi, Bivas Sahadevan, Vignesh Chen, Chia-Yuan |
author_facet | Panigrahi, Bivas Sahadevan, Vignesh Chen, Chia-Yuan |
author_sort | Panigrahi, Bivas |
collection | PubMed |
description | The artificial ciliary motion has been known not to be hydrodynamically optimal, limiting their associated applications in the microscale flow domain. One of the major hurdles of contemporary artificial cilia is its structural rigidity, which restricts their flexibility. To address this issue, this work proposed a shape-programmable artificial cilia design with distinctive polydimethylsiloxane (PDMS) and magnetic segments distributed throughout the structure, which provided precise control for time-spatial modulation of the whole artificial cilia structure under external magnetic actuation. For the fabrication of the proposed multi-segment artificial cilia, a facile microfabrication process with stepwise mold blocking followed by the PDMS and magnetic composite casting was adopted. The hydrodynamic analysis further elucidated that the proposed artificial cilia beating induced significant flow disturbance within the flow field, and the associated application was demonstrated through an efficient mixing operation. |
format | Online Article Text |
id | pubmed-8605101 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-86051012021-11-24 Shape-programmable artificial cilia for microfluidics Panigrahi, Bivas Sahadevan, Vignesh Chen, Chia-Yuan iScience Article The artificial ciliary motion has been known not to be hydrodynamically optimal, limiting their associated applications in the microscale flow domain. One of the major hurdles of contemporary artificial cilia is its structural rigidity, which restricts their flexibility. To address this issue, this work proposed a shape-programmable artificial cilia design with distinctive polydimethylsiloxane (PDMS) and magnetic segments distributed throughout the structure, which provided precise control for time-spatial modulation of the whole artificial cilia structure under external magnetic actuation. For the fabrication of the proposed multi-segment artificial cilia, a facile microfabrication process with stepwise mold blocking followed by the PDMS and magnetic composite casting was adopted. The hydrodynamic analysis further elucidated that the proposed artificial cilia beating induced significant flow disturbance within the flow field, and the associated application was demonstrated through an efficient mixing operation. Elsevier 2021-10-28 /pmc/articles/PMC8605101/ /pubmed/34825146 http://dx.doi.org/10.1016/j.isci.2021.103367 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Panigrahi, Bivas Sahadevan, Vignesh Chen, Chia-Yuan Shape-programmable artificial cilia for microfluidics |
title | Shape-programmable artificial cilia for microfluidics |
title_full | Shape-programmable artificial cilia for microfluidics |
title_fullStr | Shape-programmable artificial cilia for microfluidics |
title_full_unstemmed | Shape-programmable artificial cilia for microfluidics |
title_short | Shape-programmable artificial cilia for microfluidics |
title_sort | shape-programmable artificial cilia for microfluidics |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605101/ https://www.ncbi.nlm.nih.gov/pubmed/34825146 http://dx.doi.org/10.1016/j.isci.2021.103367 |
work_keys_str_mv | AT panigrahibivas shapeprogrammableartificialciliaformicrofluidics AT sahadevanvignesh shapeprogrammableartificialciliaformicrofluidics AT chenchiayuan shapeprogrammableartificialciliaformicrofluidics |