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Dihydropyrimidine dehydrogenase (DPYD) gene c.1627A>G A/G and G/G genotypes are risk factors for lymph node metastasis and distant metastasis of colorectal cancer

BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) acts as the key enzyme catabolizing pyrimidines, and may affect the tumor progression. DPYD gene mutations affect DPD activity. The relationship between DPYD IVS14+1G>A, c.1627A>G, c.85T>C and lymph node metastasis (LNM) and distant metastas...

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Detalles Bibliográficos
Autores principales:	Zeng, Juanzi, Wu, Heming, Huang, Qingyan, Li, Jiaquan, Yu, Zhikang, Zhong, Zhixiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605172/ https://www.ncbi.nlm.nih.gov/pubmed/34612540 http://dx.doi.org/10.1002/jcla.24023

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