Antinuclear antibodies produced in HLA-DR transgenic humanized mice developed chronic graft-versus-host disease

BACKGROUND: Chronic graft versus host disease (GVHD) has been reported in humanized mice after the implantation of human hematopoietic stem cells (hu-HSC). As such, humanized mice have been applied to a mouse model of chronic GVHD; however, B-cell activation and autoantibody production did not occur...

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Detalles Bibliográficos
Autores principales: Tsuzuki, Hiroshi, Nagatsuka, Yasuko, Iwata, Mitsuhiro, Kitamura, Noboru, Nagasawa, Yosuke, Matsumoto, Taro, Ito, Ryoji, Takahashi, Takeshi, Ito, Mamoru, Nakamura, Hideki, Takei, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605287/
https://www.ncbi.nlm.nih.gov/pubmed/34825089
http://dx.doi.org/10.1016/j.heliyon.2021.e08380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605287/
https://www.ncbi.nlm.nih.gov/pubmed/34825089
http://dx.doi.org/10.1016/j.heliyon.2021.e08380

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