The tumour suppressor CCDC6 is involved in ROS tolerance and neoplastic transformation by evading ferroptosis

Coiled-coil domain containing 6 (CCDC6) is a tumour suppressor gene involved in apoptosis and DNA damage response. CCDC6 is known to be functionally impaired upon gene fusions, somatic mutations, and altered protein turnover in several tumours. Testicular germ cell tumours are among the most common...

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Detalles Bibliográficos
Autores principales: Morra, Francesco, Merolla, Francesco, Zito Marino, Federica, Catalano, Rosaria, Franco, Renato, Chieffi, Paolo, Celetti, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605351/
https://www.ncbi.nlm.nih.gov/pubmed/34841108
http://dx.doi.org/10.1016/j.heliyon.2021.e08399

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