Determining folding and binding properties of the C‐terminal SH2 domain of SHP2

SH2 domains are a class of protein–protein interaction modules with the function to recognize and bind sequences characterized by the presence of a phosphorylated tyrosine. SHP2 is a protein phosphatase involved in the Ras‐ERK1/2 signaling pathway that possess two SH2 domains, namely, N‐SH2 and C‐SH...

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Detalles Bibliográficos
Autores principales: Nardella, Caterina, Malagrinò, Francesca, Pagano, Livia, Rinaldo, Serena, Gianni, Stefano, Toto, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Full‐Length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605372/
https://www.ncbi.nlm.nih.gov/pubmed/34605082
http://dx.doi.org/10.1002/pro.4201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605372/
https://www.ncbi.nlm.nih.gov/pubmed/34605082
http://dx.doi.org/10.1002/pro.4201

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