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Determining folding and binding properties of the C‐terminal SH2 domain of SHP2
SH2 domains are a class of protein–protein interaction modules with the function to recognize and bind sequences characterized by the presence of a phosphorylated tyrosine. SHP2 is a protein phosphatase involved in the Ras‐ERK1/2 signaling pathway that possess two SH2 domains, namely, N‐SH2 and C‐SH...
Autores principales: | Nardella, Caterina, Malagrinò, Francesca, Pagano, Livia, Rinaldo, Serena, Gianni, Stefano, Toto, Angelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605372/ https://www.ncbi.nlm.nih.gov/pubmed/34605082 http://dx.doi.org/10.1002/pro.4201 |
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