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Structure based prediction of a novel GPR120 antagonist based on pharmacophore screening and molecular dynamics simulations
The G-protein coupled receptor, GPR120, has ubiquitous expression and multifaceted roles in modulating metabolic and anti-inflammatory processes. Recent implications of its role in cancer progression have presented GPR120 as an attractive oncogenic drug target. GPR120 gene knockdown in breast cancer...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605389/ https://www.ncbi.nlm.nih.gov/pubmed/34849208 http://dx.doi.org/10.1016/j.csbj.2021.11.005 |