Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir

Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunolog...

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Autores principales: Foti, Caterina, Favoino, Elvira, Scarasciulli, Maria, Colacicco, Anna Maria, Jahantigh, Hamidreza, Stufano, Angela, Lovreglio, Piero, Mascia, Paola, Barlusconi, Chiara, Perosa, Federico, Romita, Paolo, Calvario, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605419/
https://www.ncbi.nlm.nih.gov/pubmed/34840952
http://dx.doi.org/10.1016/j.idcr.2021.e01331
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author Foti, Caterina
Favoino, Elvira
Scarasciulli, Maria
Colacicco, Anna Maria
Jahantigh, Hamidreza
Stufano, Angela
Lovreglio, Piero
Mascia, Paola
Barlusconi, Chiara
Perosa, Federico
Romita, Paolo
Calvario, Agata
author_facet Foti, Caterina
Favoino, Elvira
Scarasciulli, Maria
Colacicco, Anna Maria
Jahantigh, Hamidreza
Stufano, Angela
Lovreglio, Piero
Mascia, Paola
Barlusconi, Chiara
Perosa, Federico
Romita, Paolo
Calvario, Agata
author_sort Foti, Caterina
collection PubMed
description Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunologic response. Our report evaluated EBV-specific T cell responses by IFN- γ ELISPOT assay, which revealed defective EBV specific immunological response.
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spelling pubmed-86054192021-11-26 Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir Foti, Caterina Favoino, Elvira Scarasciulli, Maria Colacicco, Anna Maria Jahantigh, Hamidreza Stufano, Angela Lovreglio, Piero Mascia, Paola Barlusconi, Chiara Perosa, Federico Romita, Paolo Calvario, Agata IDCases Case Report Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunologic response. Our report evaluated EBV-specific T cell responses by IFN- γ ELISPOT assay, which revealed defective EBV specific immunological response. Elsevier 2021-11-11 /pmc/articles/PMC8605419/ /pubmed/34840952 http://dx.doi.org/10.1016/j.idcr.2021.e01331 Text en © 2021 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Foti, Caterina
Favoino, Elvira
Scarasciulli, Maria
Colacicco, Anna Maria
Jahantigh, Hamidreza
Stufano, Angela
Lovreglio, Piero
Mascia, Paola
Barlusconi, Chiara
Perosa, Federico
Romita, Paolo
Calvario, Agata
Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_full Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_fullStr Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_full_unstemmed Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_short Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
title_sort chronic-relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced ebv-specific t cell response using enzyme-linked immunospot (elispot) assay successfully treated with valaciclovir
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605419/
https://www.ncbi.nlm.nih.gov/pubmed/34840952
http://dx.doi.org/10.1016/j.idcr.2021.e01331
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