Making memories with Bcl-6

For over a decade, mutual antagonism between the transcriptional repressors Bcl-6 and Blimp-1 has been appreciated as a key mechanistic determinant of lymphoid differentiation programs. Now, in this issue of JEM, Ciucci et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20202343) demonstrate tha...

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Detalles Bibliográficos
Autores principales: Read, Kaitlin A., Oestreich, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605494/
https://www.ncbi.nlm.nih.gov/pubmed/34792529
http://dx.doi.org/10.1084/jem.20212177
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author Read, Kaitlin A.
Oestreich, Kenneth J.
author_facet Read, Kaitlin A.
Oestreich, Kenneth J.
author_sort Read, Kaitlin A.
collection PubMed
description For over a decade, mutual antagonism between the transcriptional repressors Bcl-6 and Blimp-1 has been appreciated as a key mechanistic determinant of lymphoid differentiation programs. Now, in this issue of JEM, Ciucci et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20202343) demonstrate that this relationship is "central" to the generation of T cell memory.
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spelling pubmed-86054942022-07-03 Making memories with Bcl-6 Read, Kaitlin A. Oestreich, Kenneth J. J Exp Med Insights For over a decade, mutual antagonism between the transcriptional repressors Bcl-6 and Blimp-1 has been appreciated as a key mechanistic determinant of lymphoid differentiation programs. Now, in this issue of JEM, Ciucci et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20202343) demonstrate that this relationship is "central" to the generation of T cell memory. Rockefeller University Press 2021-11-18 /pmc/articles/PMC8605494/ /pubmed/34792529 http://dx.doi.org/10.1084/jem.20212177 Text en © 2021 Read and Oestreich https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Read, Kaitlin A.
Oestreich, Kenneth J.
Making memories with Bcl-6
title Making memories with Bcl-6
title_full Making memories with Bcl-6
title_fullStr Making memories with Bcl-6
title_full_unstemmed Making memories with Bcl-6
title_short Making memories with Bcl-6
title_sort making memories with bcl-6
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605494/
https://www.ncbi.nlm.nih.gov/pubmed/34792529
http://dx.doi.org/10.1084/jem.20212177
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