Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function

Synaptic connectivity within adult circuits exhibits a remarkable degree of cellular and subcellular specificity. We report that the axon guidance receptor Robo2 plays a role in establishing synaptic specificity in hippocampal CA1. In vivo, Robo2 is present and required postsynaptically in CA1 pyram...

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Detalles Bibliográficos
Autores principales: Blockus, Heike, Rolotti, Sebi V., Szoboszlay, Miklos, Peze-Heidsieck, Eugénie, Ming, Tiffany, Schroeder, Anna, Apostolo, Nuno, Vennekens, Kristel M., Katsamba, Phinikoula S., Bahna, Fabiana, Mannepalli, Seetha, Ahlsen, Goran, Honig, Barry, Shapiro, Lawrence, de Wit, Joris, Losonczy, Attila, Polleux, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605498/
https://www.ncbi.nlm.nih.gov/pubmed/34686348
http://dx.doi.org/10.1016/j.celrep.2021.109828

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