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Fibroblast pyruvate carboxylase is required for collagen production in the tumor microenvironment

The aberrant production of collagen by fibroblasts is a hallmark of many solid tumors and can influence cancer progression. How the mesenchymal cells in the tumor microenvironment maintain their production of extracellular matrix proteins as the vascular delivery of glutamine and glucose becomes com...

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Detalles Bibliográficos
Autores principales: Schwörer, Simon, Pavlova, Natalya N., Cimino, Francesco V., King, Bryan, Cai, Xin, Sizemore, Gina M., Thompson, Craig B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606002/
https://www.ncbi.nlm.nih.gov/pubmed/34764457
http://dx.doi.org/10.1038/s42255-021-00480-x

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