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Suppressive role of E3 ubiquitin ligase FBW7 in type I diabetes in non-obese diabetic mice through mediation of ubiquitination of EZH2

The current study tried to uncover the molecular mechanism of E3 ubiquitin ligase F-box and WD repeat domain-containing 7 (FBW7) in a heritable autoimmune disease, type I diabetes (T1D). After streptozotocin-induced T1D model establishment in non-obese diabetic (NOD) mouse, the protein expression of...

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Detalles Bibliográficos
Autores principales:	Guo, Yingxue, Li, Junfeng, Fan, Shuang, Hu, Qibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606006/ https://www.ncbi.nlm.nih.gov/pubmed/34802056 http://dx.doi.org/10.1038/s41420-021-00605-x

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