When metabolic prowess is too much of a good thing: how carbon catabolite repression and metabolic versatility impede production of esterified α,ω-diols in Pseudomonas putida KT2440

BACKGROUND: Medium-chain-length α,ω-diols (mcl-diols) are important building blocks in polymer production. Recently, microbial mcl-diol production from alkanes was achieved in E. coli (albeit at low rates) using the alkane monooxygenase system AlkBGTL and esterification module Atf1. Owing to its rem...

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Detalles Bibliográficos
Autores principales: Lu, Chunzhe, Batianis, Christos, Akwafo, Edward Ofori, Wijffels, Rene H., Martins dos Santos, Vitor A. P., Weusthuis, Ruud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606055/
https://www.ncbi.nlm.nih.gov/pubmed/34801079
http://dx.doi.org/10.1186/s13068-021-02066-x

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