Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density

LIN28A overexpression has been identified in malignant brain tumors called embryonal tumors with multilayered rosettes (ETMR) but its specific role during brain development remains largely unknown. Radial glia cells of the ventricular zone (VZ) are proposed as a cell of origin for ETMR. We asked whe...

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Detalles Bibliográficos
Autores principales: Middelkamp, Maximilian, Ruck, Lisa, Krisp, Christoph, Sumisławski, Piotr, Mohammadi, Behnam, Dottermusch, Matthias, Meister, Valerie, Küster, Lukas, Schlüter, Hartmut, Windhorst, Sabine, Neumann, Julia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606090/
https://www.ncbi.nlm.nih.gov/pubmed/34801069
http://dx.doi.org/10.1186/s40478-021-01289-1

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