Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease

Elevated circulating activity of adenosine deaminase 2 (ADA2) is associated with liver fibrosis in nonalcoholic fatty liver disease (NAFLD). In the liver of NAFLD patients, ADA2-positive portal macrophages are significantly associated with the degree of liver fibrosis. These liver macrophages are CD...

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Detalles Bibliográficos
Autores principales: Tiwari-Heckler, Shilpa, Yee, Eric U., Yalcin, Yusuf, Park, Jiwoon, Nguyen, Duc-Huy T., Gao, Wenda, Csizmadia, Eva, Afdhal, Nezam, Mukamal, Kenneth J., Robson, Simon C., Lai, Michelle, Schwartz, Robert E., Jiang, Z. Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606247/
https://www.ncbi.nlm.nih.gov/pubmed/34706243
http://dx.doi.org/10.1016/j.celrep.2021.109897

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