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Synthesis and evaluation of enantiomers of hydroxychloroquine against SARS-CoV-2 in vitro

Since the end of 2019, the outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has evolved into a global pandemic. There is an urgent need for effective and low-toxic antiviral drugs to remedy Remdesivir’s limitation. Hydroxychloroquine, a broad spectrum anti-viral drug, showed...

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Detalles Bibliográficos
Autores principales: Ni, Yong, Liao, Jinbiao, Qian, Zhenlong, Wu, Chunxiu, Zhang, Xiangyu, Zhang, Ji, Xie, Youhua, Jiang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606320/
https://www.ncbi.nlm.nih.gov/pubmed/34875467
http://dx.doi.org/10.1016/j.bmc.2021.116523