An accomplice more than a mere victim: The impact of β-cell ER stress on type 1 diabetes pathogenesis

BACKGROUND: Pancreatic β-cells are the insulin factory of an organism with a mission to regulate glucose homeostasis in the body. Due to their high secretory activity, β-cells rely on a functional and intact endoplasmic reticulum (ER). Perturbations to ER homeostasis and unmitigated stress lead to β...

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Detalles Bibliográficos
Autores principales: Sahin, Gulcan Semra, Lee, Hugo, Engin, Feyza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606542/
https://www.ncbi.nlm.nih.gov/pubmed/34728341
http://dx.doi.org/10.1016/j.molmet.2021.101365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606542/
https://www.ncbi.nlm.nih.gov/pubmed/34728341
http://dx.doi.org/10.1016/j.molmet.2021.101365

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