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An accomplice more than a mere victim: The impact of β-cell ER stress on type 1 diabetes pathogenesis
BACKGROUND: Pancreatic β-cells are the insulin factory of an organism with a mission to regulate glucose homeostasis in the body. Due to their high secretory activity, β-cells rely on a functional and intact endoplasmic reticulum (ER). Perturbations to ER homeostasis and unmitigated stress lead to β...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606542/ https://www.ncbi.nlm.nih.gov/pubmed/34728341 http://dx.doi.org/10.1016/j.molmet.2021.101365 |