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GSDMD Mediates LPS-Induced Septic Myocardial Dysfunction by Regulating ROS-dependent NLRP3 Inflammasome Activation

Myocardial dysfunction is a serious consequence of sepsis and contributes to high mortality. Currently, the molecular mechanism of myocardial dysfunction induced by sepsis remains unclear. In the present study, we investigated the role of gasdermin D (GSDMD) in cardiac dysfunction in septic mice and...

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Detalles Bibliográficos
Autores principales:	Dai, Shanshan, Ye, Bozhi, Zhong, Lingfeng, Chen, Yanghao, Hong, Guangliang, Zhao, Guangju, Su, Lan, Lu, Zhongqiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606561/ https://www.ncbi.nlm.nih.gov/pubmed/34820388 http://dx.doi.org/10.3389/fcell.2021.779432

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