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Epigenetic Regulator KDM4D Restricts Tumorigenesis via Modulating SYVN1/HMGB1 Ubiquitination Axis in Esophageal Squamous Cell Carcinoma

BACKGROUND: Increasing researches have been reported that epigenetic alterations play critical roles in ESCC development. However, the role of the histone demethylase KDM4D in ESCC tumorigenesis is poorly investigated. This study aims to discover the underlying mechanisms between KDM4D and ESCC prog...

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Detalles Bibliográficos
Autores principales: Yao, Wenjian, Wang, Jianjun, Zhu, Li, Jia, Xiangbo, Xu, Lei, Tian, Xia, Hu, Shuai, Wu, Sen, Wei, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606580/
https://www.ncbi.nlm.nih.gov/pubmed/34820329
http://dx.doi.org/10.3389/fonc.2021.761346