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HIF1 and ID1 Interplay Confers Adaptive Survival to HIF1α-Inhibition

Hypoxia is a universal pathological feature of solid tumors. Hypoxic tumor cells acquire metastatic and lethal phenotypes primarily through the activities of hypoxia-inducible factor 1 alpha (HIF1α). Therefore, HIF1α is considered as a promising therapeutic target. However, HIF inhibitors have not p...

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Detalles Bibliográficos
Autores principales:	Geng, Hao, Ko, Hyun-Kyung, Pittsenbarger, Janet, Harvey, Christopher T., Xue, Changhui, Liu, Qiong, Wiens, Sadie, Kachhap, Sushant K., Beer, Tomasz M., Qian, David Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606652/ https://www.ncbi.nlm.nih.gov/pubmed/34820369 http://dx.doi.org/10.3389/fcell.2021.724059

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