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Structure‐guided envelope trimer design in HIV‐1 vaccine development: a narrative review

INTRODUCTION: The development of a human immunodeficiency virus 1 (HIV‐1) vaccine remains a formidable challenge. An effective vaccine likely requires the induction of broadly neutralizing antibodies (bNAbs), which likely involves the use of native‐like HIV‐1 envelope (Env) trimers at some or all st...

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Detalles Bibliográficos
Autores principales: Derking, Ronald, Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606863/
https://www.ncbi.nlm.nih.gov/pubmed/34806305
http://dx.doi.org/10.1002/jia2.25797