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Optimization of Initial Dose Regimen for Sirolimus in Pediatric Patients With Lymphangioma

Sirolimus is an effective oral treatment for pediatric patients with lymphangioma. The present clinical study in 15 children (0.12–16.39 years of age) examines the effects of underlying factors on sirolimus concentrations through application of a population pharmacokinetic model. Using Monte Carlo s...

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Detalles Bibliográficos
Autores principales:	Chen, Xiao, Wang, Dongdong, Wang, Guangfei, Huang, Yidie, Yu, Xin, Lu, Jinmiao, Zhai, Xiaowen, Xu, Hong, Li, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606893/ https://www.ncbi.nlm.nih.gov/pubmed/34819851 http://dx.doi.org/10.3389/fphar.2021.668952

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