Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report

A 48-year-old Caucasian woman with history of multiple sclerosis (MS) presented with erythematous papulonodular lesions in her extremities and trunk. She was being treated with glatiramer acetate (GA) for the past 10 years and the glatiramoid, Glatopa, for 2 years prior to this presentation. A skin...

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Autores principales: Shirani, Afsaneh, Dalton, Scott R, Avery, Eric J, Arcot Jayagopal, Lakshman, Meyer, Christina, Stuve, Olaf, Zabad, Rana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606967/
https://www.ncbi.nlm.nih.gov/pubmed/34819759
http://dx.doi.org/10.1177/11795735211053784
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author Shirani, Afsaneh
Dalton, Scott R
Avery, Eric J
Arcot Jayagopal, Lakshman
Meyer, Christina
Stuve, Olaf
Zabad, Rana
author_facet Shirani, Afsaneh
Dalton, Scott R
Avery, Eric J
Arcot Jayagopal, Lakshman
Meyer, Christina
Stuve, Olaf
Zabad, Rana
author_sort Shirani, Afsaneh
collection PubMed
description A 48-year-old Caucasian woman with history of multiple sclerosis (MS) presented with erythematous papulonodular lesions in her extremities and trunk. She was being treated with glatiramer acetate (GA) for the past 10 years and the glatiramoid, Glatopa, for 2 years prior to this presentation. A skin biopsy showed CD30(+) lymphoproliferative disorder consistent with lymphomatoid papulosis (LyP). Three weeks after stopping Glatopa, her skin lesions were improved. It remains unclear whether GA’s or Glatopa’s capability to alter T-cell differentiation, may have a link with LyP. This case report is a reminder to be vigilant for skin lesions in patients with MS.
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spelling pubmed-86069672021-11-23 Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report Shirani, Afsaneh Dalton, Scott R Avery, Eric J Arcot Jayagopal, Lakshman Meyer, Christina Stuve, Olaf Zabad, Rana J Cent Nerv Syst Dis Case Report A 48-year-old Caucasian woman with history of multiple sclerosis (MS) presented with erythematous papulonodular lesions in her extremities and trunk. She was being treated with glatiramer acetate (GA) for the past 10 years and the glatiramoid, Glatopa, for 2 years prior to this presentation. A skin biopsy showed CD30(+) lymphoproliferative disorder consistent with lymphomatoid papulosis (LyP). Three weeks after stopping Glatopa, her skin lesions were improved. It remains unclear whether GA’s or Glatopa’s capability to alter T-cell differentiation, may have a link with LyP. This case report is a reminder to be vigilant for skin lesions in patients with MS. SAGE Publications 2021-11-20 /pmc/articles/PMC8606967/ /pubmed/34819759 http://dx.doi.org/10.1177/11795735211053784 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Shirani, Afsaneh
Dalton, Scott R
Avery, Eric J
Arcot Jayagopal, Lakshman
Meyer, Christina
Stuve, Olaf
Zabad, Rana
Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_full Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_fullStr Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_full_unstemmed Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_short Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_sort lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid glatopa for multiple sclerosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606967/
https://www.ncbi.nlm.nih.gov/pubmed/34819759
http://dx.doi.org/10.1177/11795735211053784
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