E7-Targeted Nanotherapeutics for Key HPV Afflicted Cervical Lesions by Employing CRISPR/Cas9 and Poly (Beta-Amino Ester)

INTRODUCTION: Persistent HR-HPV (high-risk human papillomavirus) infection is the main cause of cervical cancer. The HPV oncogene E7 plays a key role in HPV tumorigenesis. At present, HPV preventive vaccines are not effective for patients who already have a cervical disease, and implementation of th...

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Detalles Bibliográficos
Autores principales: Xiong, Jinfeng, Tan, Songwei, Yu, Long, Shen, Hui, Qu, Shen, Zhang, Chong, Ren, Ci, Zhu, Da, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606985/
https://www.ncbi.nlm.nih.gov/pubmed/34819726
http://dx.doi.org/10.2147/IJN.S335277

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